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INTRAVENOUS IMMUNOGLOBULIN-ASSOCIATED HEART BLOCK IN A KIDNEY TRANSPLANT RECIPIENT: A RARE CARDIAC COMPLICATION

Saurabh PURI, Nidhi YADAV, Vishal BATHEJA, Bhavin MODASIA, Aditi SHARMA, Hari Shankar MESHRAM, Chandani BHAGAT, Rajendra Prasad MATHUR

Experimental and Clinical Transplantation - 2026;24(2):197-198

Department of Nephrology, Institute of Liver and Biliary Sciences, New Delhi

 

Intravenous immunoglobulin (IVIG) is extensively used in kidney transplant for desensitization, antibody-mediated rejection, and select viral or autoimmune complications. Although generally safe, adverse effects such as renal dysfunction, thromboembolism, hemolysis, and aseptic meningitis have been reported. Cardiovascular reactions, including hypotension, arrhythmias, and atrioventricular (AV) block, are rare but clinically significant. Here, we report a renal-allograft recipient who developed reversible AV block temporally related to IVIG given for BK virus-associated nephropathy.