Talat Umut Kutlu DILEK, Eren KAYA, Elif AYGÜN, Özlem PATA
Journal of the Turkish-German Gynecological Association - 2026;27(1):8-18
Objective: To share our experience of ultrasonographic evaluation of fetal anatomy in the first trimester and pregnancy follow-up in a tertiary center. Material and Methods: This retrospective study was conducted in the Acıbadem University Atakent Hospital and Acıbadem University Bakırköy Hospital Prenatal Diagnosis Units between April 2015 and December 2019. The study group included pregnant women referred for first-trimester aneuploidy screening and anomaly survey. Results: The mean maternal age was 31.28+/-4.43 years and ranged from 20-49 years. The median gestational week at which first-trimester evaluation was made was 12.4 weeks. Of 3254 cases, 55 (1.69%) had pathologic ultrasound findings in the first-trimester anomaly scan, including increased nuchal translucency (NT) value over 95th percentile in 34 fetuses (52.3%) with structural anomaly. Conclusion: Screening between 11-14 weeks of pregnancy may be an opportunity to evaluate maternal health and detect severe fetal anomalies.