HÜMEYRA YAKA, SELMA PEKGÖR, HALUK YAKA, MUSTAFA ÖZER
Annals of Clinical and Analytical Medicine - 2024;15(10):721-724
Aim: The 2D:4D ratio, which is the ratio of the length of the index finger to the length of the ring finger, is negatively correlated with prenatal exposure to testosterone. The aim of this study was to investigate the relationship between 2D:4D ratio and smoking addiction. Material and methods: 81 patients who were admitted to the orthopaedics and traumatology outpatient clinic and who had smoking addiction were included in the study. 102 patients without a history of smoking addiction were determined as the control group. The second and fourth finger lengths of both groups were measured. The data obtained from both groups were compared statistically. Results: Mean left hand and right hand 2D:4D ratios was significantly lower in patients with smoking addiction compared to the control group (P<0.001, P=0.03 respectively). Both left hand and right hand 2D:4D ratios were significantly lower in male smokers than in male controls (P<0.001, P=0.007 respectively). Left hand 2D:4D ratio was significantly lower in female smokers than in the female control group, while there was no significant difference between right hand 2D:4D ratio (P<0.001, P=0.113 respectively). Discussion: Low 2D:4D ratio, which is an indicator of high testosterone exposure in the prenatal period, seems to be associated with smoking addiction. The 2D:4D ratio may be useful in assessing the risk of smoking addiction in individuals in childhood and adolescence. Knowing that individuals with low 2D:4D have a higher addiction potential may be useful in addiction prevention and addiction treatment.
