NURULLAH PEKER SERHAT EGE
Northwestern Medical Journal - 2025;5(2):93-97
Aim: The aim of this study is to compare the diagnostic accuracy of follicular stimulating hormone (FSH) in different age groups of poor ovarian reserve (POR) infertile patients. Material and methods: The records of infertile patients who presented to a tertiary center hospital infertility outpatient clinic were retrospectively analysed. The patients were divided into two groups: those between the ages of 20-29 were considered as group 1, and those between the ages of 30-39 were considered as group 2. FSH specificity and sensitivity were compared in patients with (POR) with antimullerian hormone (AMH) values below <1 ng/mLThe specificity, sensitivity, and accuracy of the FSH assay as a diagnostic tool for determining reduced OR in females with POR were compared and predicted using ROC curve analysis. Results: A total of 102 infertile patients were assessed. Those between the ages of 20-29 were considered as group 1, and those between the ages of 30-39 were considered as group 2. The avarages FSH levels for each group were 9.73 ± 3.17 and 10.06 ± 8.74, respectively (p value = 0.85). The sensitivity, accuracy, and specificity of the FSH assay were, 85%, 78%, and 68%, respectively (p=0,001). In group 2, FSH values may be more meaningful for evaluating the ovarian reserve. Conclusion: FSH was not correlated with AMH and antral follicule count (AFC). In the age-specific FSH assessment showed that FSH is still not a specific marker in POR. This study concluded that FSH and age have a weak correlation with the number of follicles restored and the number of oocytes retrieved.
