Lakshmi Radhakrishnan, Ramita Mukherjee, Brijesh Kumar Singh, Yashika Maheswari, Yamini Dharmashaktu, Asuri Krishna, Vuthaluru Seenu
European Journal of Breast Health - 2026;22(1):102-105
Invasive lobular carcinoma (ILC) is the second most common histologic subtype of invasive breast cancer, accounting for 5-15% of this type. Though its unique propensity to metastasize to the extra-hepatic gastrointestinal tract is well known, isolated colonic metastasis without disseminated or locoregional recurrence is rare. These isolated lesions may be amenable to curative treatment with a better prognosis. Here we present the diagnostic challenge faced while managing the case of a 62-year-old female who was treated for estrogen receptor-positive ILC of the breast 10-years previously, who presented with an ileocecal mass, which on biopsy revealed metastatic ILC. She was treated with laparoscopic hemicolectomy followed by hormonal therapy and remained asymptomatic at 18-months follow-up.
