KOLONOSKOPİK FEKAL MİKROBİATA TRANSPLANTASYONU SIRASINDA ANEZTEZİ

AYŞEGÜL CEYLAN, MEHMET BURAK EŞKİN, YUSUF SERDAR SAKİN, AHMET UYGUN

Koru Proceedings - 2019;7(3):1-5

Turkish Ministry of Health Gulhane Teaching and Research Hospital, Anesthesiology and Reanimation Clinic, Ankara, TURKEY

 

Aim We believe that sharing our experience with anesthesia in this method of treatment, which we think will be more common in the world and in the future, may be of interest to other anesthesiologists and gastroenterologists. Although there are many published articles about fecal transplantation, no reports have been released about anesthetic applications yet. Methods: A total of 80 patients who underwent FMT with colonoscopy were evaluated retrospectively. During colonoscopic procedure, 1% propofol 1-2 mg/ kg, midazolam 0,02 mg/kg and fentanyl 0,5-1 mcg/kg were administered via intravenous (IV) bolus injection for sedation and analgesia. Patients’ pulse rate, mean blood pressure, peripheral oxygen saturation (SpO2) were recorded before, during, and after the procedure. Results: Of all patients, intraoperative values of SPO2, mean arterial pressure and pulse/minute were significantly lower than preoperative values. However, no hypoxia or hypotension occurred which would require a general anesthesia instead of sedation. Colonoscopy patients, mean wake-up time was 18,66 minutes. Postoperative mild abdominal pain VAS score was found to be 2.7. No complications were observed in the patients. Conclusion Using propofol in combination with opioids and benzodiazepines with lower and more safe doses appears to be a significant advantage of combination therapy especially in colonoscopy.