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LC-MS ANALYSIS OF CORMS OF COLCHICUM HIEROSOLYMITANUM (COLCHICACEAE)

FERAS ALALİ, ABDULLAH EL-ALALİ

Acta Pharmaceutica Sciencia - 2005;47(2):143-150

Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan

 

LC-MS analysis of corms of Colchicum hierosolymitanum Feinbr (Colchicaceae) was conducted using a single quadrupole mass analyzer equipped with (+)-APCI ionizing interface. (-)-Colchicine (7) and eight (1-6, 8, 9) natural analogues were detected and identified in the alkaloid rich fraction. These compounds are reported for the first time in C. hierosolymitanum.