HANEN CHAKER, SOUMAYA YAİCH, HANEN ABİD, SOUHİR KHEMİRİ, SLİM CHARFİ, MONDHER MASMOUDİ, MOHAMED BEN HMİDA, TAHYA BOUDAWARA, AFEF KHANFİR, KHAWLA KAMMOUN
Experimental and Clinical Transplantation - 2025;23(6):431-434
Long-term immunosuppression can lead to malignant tumors after kidney transplant. In this case study, we report a rare case of breast cancer occurring in a man after 33 years of kidney transplant. This 55-year-old kidney transplant patient presented with a right breast mass. The biopsy showed an infiltrating carcinoma. The immunohistochemical study was positive for estrogen. The patient underwent a right mastectomy with axillary dissection. Chemotherapy based on docetaxel and radiotherapy was started. Adjuvant treatment with tamoxifen and a switch from azathioprine to sirolimus were conducted. Follow-up showed that the patient died 24 months after presentation. Through this case, we emphasize the importance of vigilance about this rare cancer, often diagnosed at a late stage, which can negatively affect prognosis. Screening for risk factors is crucial.
