NUR DOKUZEYLÜL, SELÇUK ÖZDEN, VEDAT DAYICIOĞLU
Gynecology Obstetrics & Reproductive Medicine - 2004;10(1):27-32
OBJECTIVE: To detect maternal-perinatal mortality and morbidity in pregnant women with partial and complete (classical) HELLP syndrome. STUDY DESIGN: Forty-two pregnant women having classical triad of HELLP syndrome (i.e., H: hemolysis, EL: elevated liver enzymes, LP: low platelet), 189 pregnant women having one or two criteria of HELLP syndrome (i.e. partial HELLP syndrome) and 34 preeclamptic pregnant women without HELLP syndrome were evaluated prospectively. Cases with partial HELLP syndrome were divided in to three subgroups according to the existing criteria ( H, HEL, HLP). RESULTS: The rates of abnormal clinical, laboratory findings, need for administration of corticosteroids, need for neonatal intensive care unite were found to be increased in relationship with the increasing number of HELLP criteria. CONCLUSION: Maternal-perinatal mortality and morbidity were found to be lower in cases with partial HELLP syndrome than cases with complete HELLP syndrome, but to be higher than the cases without criteria of the syndrome. Low platelet count was found to be the most significant factor related with maternal-perinatal mortality. It may be possible to decrease maternal-perinatal mortality and morbidity by timely interference adjusted before the formation of HELLP criteria.
