Liana GABRIEL, Jorge MEJIA-CORLETTO, Beatriz BLINOV, Meredith AKERMAN, Jacklyn FRANK, Paul SAENGER
Journal of Clinical Research in Pediatric Endocrinology - 2026;18(1):42-47
Objective: Endocrine findings in premature adrenarche have been characterized by elevated dehydroepiandrosterone (DHEA) DHEA-sulfate (DHEA-S) levels in the past. Methods: We reviewed female patients, aged 4 to 8 years, with premature adrenarche who were seen at a single center between 2019 and 2023. Data were collected on the traditional androgens (DHEA and DHEA-S) and novel 11-oxo-androgens, which were measured using liquid chromatography/tandem mass spectrometry assays in commercial laboratories (Lab Corp).
