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MISLEADING METRICS? A PROSPECTIVE STUDY ON POST-VOID RESIDUAL URINE MEASUREMENT TIMING IN MEN WITH LOWER URINARY TRACT SYMPTOMS

Bayram DOGAN, Selin Ayten AKOK, Abdullah ILKTAC, Fatih GEVHER, Serkan AKINCI, Aysegul YABANCI TAK

Sakarya Tıp Dergisi - 2026;16(1):158-165

Bezmialem Vakif University, Faculty of Medicine, Department of Urology, Istanbul, Türkiye

 

Objective: This study investigates the potential discrepancy between post-void residual urine (PVR) measurements obtained immediately after uroflowmetry and those reflecting patients' usual voiding patterns, aiming to evaluate the reliability of immediate post-test measurements. Methods: This prospective study included 110 men >45 years with lower urinary tract symptoms. PVR was measured by transabdominal ultrasonography immediately after uroflowmetry (PVR0), on day 1 (PVR1), and day 7 (PVR7). Patients were grouped by pre-void bladder volume: <300 mL, 300-500 mL, >500 mL. Uroflowmetric parameters, prostate volume, PSA, IPSS, BMI, and detrusor thickness were recorded. Results: The mean age was 60.32+/-6.93 years; mean prostate volume 44.84+/-20.44 mL. In the uroflowmetry test, the mean values for Qmax, Qave, and voided volume were detected as 15.83+/-7.00 mL/sec, 6.21+/-2.62 mL/sec, and 304.15+/-157.81 mL, respectively. The mean bladder volume was 408.30+/-191.53 mL. When stratified into three groups based on bladder volume (<300 mL, 300-500 mL, and >500 mL), 26.4% of the patients had a bladder volume <300 mL, 49.1% had 300-500 mL, and 24.5% had >500 mL. The mean PVR0, PVR1, and PVR7 were 104.12+/-108.51 mL, 33.74+/-82.54 mL, and 19.59+/-47.91 mL, respectively. A comparative analysis of PVR0, PVR1, and PVR7 revealed a statistically significant decreasing trend over time: PVR7 < PVR1 < PVR0 (PVR0 vs. PVR1, p < 0.001; PVR0 vs. PVR7, p < 0.001; PVR1 vs. PVR7, p = 0.003). Conclusions: Measuring PVR at a scheduled time after natural bladder filling may yield more accurate and clinically representative data, supporting more reliable treatment planning.