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MULTIPLE MYELOMA IN A 27-YEAR-OLD: A RARE PRESENTATION WITH CUTANEOUS INVOLVEMENT AND LITERATURE INSIGHTS

OUSSAMA GRARİ, NADİR MİRY, AMİNA HİMRİ, NİSMA DOUZİ, DOUNİA ELMOUJTAHİDE, EL HOUCİNE SEBBAR, AMAL BENNANİ, MOHAMMED CHOUKRİ

International Journal of Medical Biochemistry - 2024;7(3):208-211

Department of Biochemistry, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Mohammed I University, Oujda, Morocco

 

Multiple myeloma (MM) is a hematological malignancy marked by the abnormal proliferation of plasma cells that invade the bone marrow and, in most cases, secrete a monoclonal protein. While typically diagnosed in older individuals with an average age of 70, MM is rarely observed in young adults. Here, we present a unique case of MM in a 27-year-old man with nodular lesions on the trunk, histologically confirmed as cutaneous MM. Laboratory investigations revealed acute renal impairment, hypercalcemia, and the presence of IgG-Lambda paraprotein. The myelogram confirmed plasmacytosis in more than 12% of the bone marrow mononuclear cells. This case highlights the relevance of considering MM in the differential diagnosis of young patients with unusual cutaneous manifestations.