K KALMANTİS, N SKARTADOS, A ANTSAKLİS
Gynecology Obstetrics & Reproductive Medicine - 2004;10(3):230-231
Multiple Sclerosis is an acquired inflammatory demyelinating disease of the central nervous system (CNS). Its symptomatology and course varies between the affected individuals. The frequent clinical signs and symptoms of the disease are paresis or paralysis, spasticity, disturbances in synergistic movements, cerebellar ataxia, disturbances of the constrictor muscles, disturbances of sight (postocular neuritis) and dysarthrosis. Epidemiological studies have shown that there exists a decreased activity of the illness during gestation. On the other hand, there is an increased danger of relapse during the first 3-6 months immediately postpartum. The parturient who presents with paraparesis or disturbances of the constrictor muscles needs special attention because the frequency and morbidity of urinary tract infections are increased in these patients. The administration of corticosteroids for treatment of the disease is the choice of therapy in gestation while very good results in the prevention of complications and relapse of the disease have been reported with the use of intravenous immunoglobulins (IVIG) and plasmapheresis. We summarized our experience in three pregnant women with multiple sclerosis in this report.
