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MUSCLE WEAKNESS AS A PRESENTING SYMPTOM IN ANCA-ASSOCIATED VASCULITIS

HİROSHİ OİWA, TAKASHİ KURASHİGE

European Journal of Rheumatology - 2018;5(2):139-141

Department of Rheumatology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan

 

Muscle weakness is rarely a presenting symptom of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), although the disease frequently involves the lungs, skin, neurons, and kidneys. Here we describe a case of AAV presenting with muscle weakness in which only muscle biopsy could confirm the diagnosis. The literature review, including three similar cases, suggested that patients with ANCA-associated muscle vasculitis likely had myalgia, normal levels of creatine kinase, pulmonary fibrosis, rheumatoid factor, and muscle edema on MRI.