KAMURAN ŞANLI, AYŞE NUR CEYLAN
Comprehensive Medicine - 2023;15(3):211-219
INTRODUCTION: We aimed to investigate the incidence of Mycoplasma hominis and Ureaplasma urealyticum according to age and gender and the reasons why clinicians are asked to test them. We also defined their antimicrobial susceptibility. METHODS: The characteristics of 436 patients who were requested to have Mycoplasma and Ureaplasma tests between March 2021 and March 2022 were retrospectively analyzed. The complaints of each patient, the clinic to which they applied, and other simultaneously requested urine culture, vaginal culture, urine microscopy, and urine leukocyte strip test results were evaluated individually. Antimicrobial susceptibility was evaluated for the growing U. urealyticum and M. hominis tests. Results: Testing was requested for a total of 436 patients with suspicion of U. urealyticum and M. hominis infection in a 1-year period. 94.9% of the patients, with a mean age of 38.2, had chronic urinary tract complaints. 71.1% were female, and 28.8% were male. Reproduction occurred in 30.2% of all patients. And 28.8% were U. urealyticum and 1.3% were M. hominis. Of all reproducing Ureaplasmas, 80.3% were female and 20 15.1% were male. Both urinary leukocyte microscopy and leukocyte strip testing were performed in only 204 of all patients. Mycoplasma and Ureaplasma test requests were investigated by the infectious diseases clinic in 86.6% of cases, mostly in patients with urinary complaints and urine material. U. urealyticum In the antimicrobial test, Pristinamycin and minocycline (98.4%), josamycin, roxithromycin, and erythromycin (100%), clarithromycin (96.7%), tetracycline (92%), levofloxacin (71.4%), ciprofloxacin (6.3%), clindaxacin (6%), 3 ofloxacin (15.8%) were found to be sensitive. A few (only six) Mycoplasma isolates were fully susceptible (100%) to tetracycline, minocycline, pristinamycin, and josamycin, while susceptibilities to other antimicrobial agents ranged mainly in the “moderate” or “resistant” range. DISCUSSION AND CONCLUSION: Test requests for Mycoplasma and Ureaplasma from patients are rare in our hospital, except for chronic urinary complaints. It is recommended to consider other diseases that may be caused for these microorganisms and to request laboratory tests from our laboratory for diagnosis and treatment. In addition, clinicians should request antimicrobial tests of these microorganisms, apply rational drug use, and avoid excessive antibiotic use.
