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NEPHROTIC SYNDROME AS AN UNUSUAL PRESENTATION OF HODGKIN LYMPHOMA IN A 7-YEAR-OLD BOY

KENAN DOĞAN, FATİH KİLCİ, UĞUR DEMİRSOY

Trends in Pediatrics - 2022;3(3):99-101

Kocaeli University Faculty of Medicine, Department of Pediatrics, Division of Pediatric Nephrology, Kocaeli, Türkiye

 

Hodgkin lymphoma may present with nephrotic syndrome, but this coexistence is rare. Some hypotheses have been proposed, however, the reason of is not fully known. The patient was a 7-year-old boy who presented with the complaint of edema in the legs and around the eyes. Laboratory tests revealed hypoalbuminemia, hyperlipidemia, and nephrotic range proteinuria. Hodgkin lymphoma was found in the biopsy performed due to the detection of mediastinal enlargement and lymphadenopathy on X-ray and computed tomography. At the end of chemotherapy responding to Hodgkin lymphoma, nephrotic syndrome resolved without the need for other immunosuppressant treatment. Clinicians should keep in mind that the first evidence of Hodgkin lymphoma may be a nephrotic syndrome and the importance of the use of imaging methods.