PANCREATIC SQUAMOUS CELL CARCINOMA - A RARE PRESENTATION OF NEOPLASIA

Vitorino SANTOS, Mariana MELO, Lister SANTOS, Camila SILVA, Bruna PIGNATARO, Andressa TEDESCHI

Marmara Medical Journal - 2026;39(2):166-169

Department of Internal Medicine, Catholic University (UCB) and Armed Forces Hospital (HFA), Brasília-DF, Brazil

 

Pancreatic cancer (PC) has high morbidity and mortality rates, with a five-year survival rate of less than 10%. Within this spectrum, squamous cell carcinoma (SCC) of the pancreas stands out as a rare and aggressive form, representing between 0.5% and 2% of diagnosed cases. This report describes the case of a patient in whom a lesion in the body of the pancreas was incidentally identified, and he underwent a body and tail pancreatectomy. The diagnosis of pancreatic SCC was confirmed through anatomopathological examination, adjuvant treatment with the FOLFIRINOX regimen was carried out and, after eight months of outpatient follow-up, there was no evidence of recurrence or progression of the disease. The rarity of this neoplasm impacts its management, highlighting the need for more research to improve diagnosis and treatment and, consequently, the prognosis of patients.