Emine Bihter Eniseler, Bartu Çetin, Ferhat Ekinci, Atike Pınar Erdoğan, Mustafa Şahbazlar
Journal of Oncological Sciences - 2025;11(3):284-287
Paratesticular liposarcoma is an extremely rare malignant tumor that often mimics inguinal hernia or benign scrotal masses. A 52-year-old man presented with a painless left inguinal swelling initially suspected to be an inguinal hernia. Imaging studies revealed a 6 cm lipomatous lesion extending into the scrotum. During surgery, a paratesticular mass distinct from the hernia sac was identified and excised. Histopathological examination confirmed a well-differentiated liposarcoma with close surgical margins, leading to a subsequent radical orchiectomy. The final pathology showed no residual malignancy. The patient remains disease-free during follow-up without adjuvant therapy. This case emphasizes the diagnostic challenge of paratesticular liposarcomas and the importance of surgical margin assessment to prevent recurrence.