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PCOS ANIMAL MODELS: AN APPROACH INDUCED BY DEHYDROEPIANDROSTERONE

SEDA KOÇAK

Experimental and Applied Medical Science - 2021;2(1):136-145

Ankara University, Faculty of Medicine, Department of Physiology, Ankara, Turkey

 

Polycystic ovary syndrome (PCOS) is one of the most common metabolic and endocrine diseases in women. Researchers generally use animal models in order to observe mechanisms of PCOS. One of the PCOS animal model is dehydroepiandrosterone (DHEA)-induced PCOS model. In the present review, DHEA-induced PCOS animal models are investigated according to species, age, number of groups, animal weight, DHEA amount applied, solvent, solvent amount, treatment days and injection way.