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PHIALEMONIUM OBOVATUM INFECTION OF THE RENAL ALLOGRAFT: CASE REPORT AND REVIEW OF THE LITERATURE

AMİT KUMAR SİNGH, ABHİLASH CHANDRA, SANA ISLAHİ, ANUPAM DAS, KİRANPREET MALHOTRA, NAMRATA RAO

Experimental and Clinical Transplantation - 2021;19(8):871-876

Department of Nephrology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India

 

In this case report, we describe the first case of Phialemonium obovatum infection involving the renal allograft in a recipient beyond 1 year after living renal transplant. The patient presented with a locally invasive mycetoma caused by this melanized fungus in the anterior abdominal wall, which extended during the hospital stay to involve the allograft. The fungus was identified by its characteristic micromorphological features present on potato dextrose agar and Sabourad dextrose agar and on subsequent slide cultures. The patient did not survive despite repeated surgical procedures, including partial allograft nephrectomy and broad-spectrum antifungal medications. Other cases of Phialemonium infections involving renal and stem cell transplant recipients are reviewed.