Emrullah AKAY, Fatma Ferda VERIT
Annals of Clinical and Analytical Medicine - 2026;17(4):357-362
Aim: To investigate demographic, clinical, and histopathological correlates of adenomyosis in women undergoing hysterectomy for benign gynecologic conditions. Methods: This retrospective study included 202 total abdominal hysterectomy specimens collected between 2013 and 2015. Adenomyosis was defined histologically as endometrial glands and stroma located >=2 mm below the endomyometrial junction. Clinical, demographic, and pathological variables were compared between patients with and without adenomyosis. Results: Adenomyosis was identified in 101 cases (50.0%). Patients with adenomyosis had significantly lower BMI (p=0.001), higher parity (p=0.015), and less frequent regular menstrual cycles (p<0.001). Chronic cervicitis and endometrial polyps were less common in these patients (p=0.039 and p=0.013, respectively). Multivariate logistic regression showed independent associations between adenomyosis and lower prevalence of cervicitis and polyps. Conclusion: Adenomyosis is highly prevalent in hysterectomy specimens and is associated with distinct reproductive and pathological features. Routine histopathological evaluation and increased clinical suspicion are essential, particularly in premenopausal women with nonspecific symptoms.
