Mamun Al MAHTAB, Sheikh MF AKBAR, Julio CA RUBIDO, Osamu YOSHIDA, Abul K Mohammad Faizul HUQ, Sakirul KHAN, Musarrat MAHTAB, Gerardo EG NIETO
Euroasian Journal of Hepato-Gastroenterology - 2026;16(1):124-130
Aims and background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which belongs to the coronavirus family, suddenly emerged in China and neighboring regions towards the end of 2019. It disrupted the entire world within weeks to months, and finally became a pandemic that continued for about 3 years. Patients and methods: One year after the commencement of infection, a vaccine surfaced on a global basis that imparted its effect on the progression of the infection. At the same time, symptomatic treatment was initiated to treat the patients and prevent progression to severe forms. Subsequently, antiviral drugs of different paradigms were used with mixed outcomes. Finally, immune modulators were mainly used to delay complications and reduce mortality. Results: Despite all these approaches, there have been nearly one billion infections and almost one million fatalities due to the pandemic of COVID-19. Two years after the containment of the virus, if the entire episode is considered holistically, it becomes evident that more insights are required to develop preventive and therapeutic measures against the sudden appearance of some microbe. Conclusion: This is the initial theological approach, and more sophisticated drugs may be developed based on this principle.
