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PRIMARY ANGLE-CLOSURE GLAUCOMA: PATHOPHYSIOLOGY, DIAGNOSTIC APPROACHES, AND MANAGEMENT STRATEGIES - A NARRATIVE REVIEW

Rashmi SINGH, Ragni KUMARI

The Ulutas Medical Journal - 2026;12(1):7-15

Department of Optometry, Uttar Pradesh University of Medical Sciences (UPUMS), Saifai, Etawah, Uttar Pradesh, India

 

Primary angle-closure glaucoma (PACG) is a major cause of irreversible blindness worldwide, particularly in Asian populations. It represents the most severe form of primary angle-closure disease (PACD) and is characterized by obstruction of the anterior chamber angle, leading to elevated intraocular pressure (IOP) and glaucomatous optic neuropathy. PACG is often asymptomatic in early stages, resulting in delayed diagnosis and management. The article reviews the epidemiology, risk factors, pathophysiology, diagnostic approaches, and management strategies of primary angle-closure glaucoma.