MEHMET GÜL, MEHMET CİHAN YAVAŞ, SERKAN DÜNDAR
International Dental Research - 2019;9(3):119-126
Aim: The purpose of this study was to determine whether extremely low frequency electric and magnetic field (ELF-EMF) had any detrimental effects on periodontal tissue and to investigate, histologically and immunohistochemically whether melatonin (MLT) and Ganoderma lucidum (GL) had a protective role against these detrimental effects. Methodology: A total of 56 adults, male Wistar Albino rats were used in this study. Rats were divided into 7 equal groups and exposed to ELFEMF, which was produced by a high voltage source, 8 hours / day for 26 days. GL (20 mg / kg / day) and MLT (10 mg / kg / day) were administered by the oral gavage and intraperitoneal method. Results: Fibrous degeneration in the periodontal membrane, inflammatory cell infiltration, connective tissue fiber organization, dilation, and hemorrhage in the blood vessels changes were determined in the periodontal tissue of the rats in groups I and IV. A statistically significant difference was determined in the groups treated with MLT and GL (p<0.05). Conclusions: It has been determined that ELF-EMF exposure causes histological changes in the periodontal tissue of rats and that MLT and GL may protect against these effects.
