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ADR Yönetimi
ADR Yönetimi

PULMONARY INVOLVEMENT IN BRUCELLOSIS, A RARE COMPLICATION OF RENAL TRANSPLANT: CASE REPORT AND BRIEF REVIEW

NURETTİN AY, SAFAK KAYA, MELİH ANİL, VAHHAC ALP, UNAL BEYAZİT, ENVER YUKSEL, RAMAZAN DANİS

Experimental and Clinical Transplantation - 2018;16(6):757-760

Transplantation Center, Diyarbakır Education and Research Hospital, Diyarbakır Gazi Yaşargil Training and Research Hospital, Diyarbakır, Turkey

 

Brucellosis, a disease endemic in many countries including Turkey, is a systemic infectious disease. Brucellosis is rare in renal transplant recipients. Only 4 cases have been reported in the literature. In this report, we describe the clinical manifestations and laboratory findings of a brucellosis case with pulmonary involvement in a renal transplant recipient. A 20-year-old man who had a living-donor kidney transplant 4 months earlier presented to our transplant clinic with fever, cough, and right flank pain. Clarithromycin and ceftriaxone were started for the diagnosis of pneumonia. However, piperacillin/tazobactam, mero¬penem plus teicoplanin, and antituberculosis treatment were continued because the patient was unresponsive to the initial therapy. Serum Brucella agglutination titer was found to be 1/320. Treatment was started with a 6-week course of oral doxycycline and rifampin, resulting in cure. Brucellosis and especially its pulmonary involvement are rare after kidney transplant. However, in endemic areas, it should be considered as it mimics several other infectious diseases.