Ahmet ÇAMTOSUN, Ömer Faruk YILDIRIM, Hasan GÖKÇE, Özlem DALDA, Murat YILMAZ, Harun BARUTÇU
Cyprus Journal of Medical Sciences - 2026;11(4):329-333
Breast cancer (BC) is the most common cancer in women, and approximately 317,000 new cases are expected to be diagnosed in the United States in 2025. Lymph nodes, bones, lungs, liver, and brain are common target organs for BC metastasis. Metastasis to the bladder is extremely rare, with approximately 70 cases reported in the literature. A 76-year-old female patient underwent a right total mastectomy by the general surgery team approximately 25 years ago for a mass in the right breast. The patient presented to the urology outpatient clinic with complaints of hematuria and dysuria. Imaging revealed a solid mass measuring approximately 6.5x3.5 cm, protruding into the bladder lumen from the left anterolateral wall, with a distinct soft-tissue component anteriorly extending into the perivesical fatty planes (possible bladder tumor). Based on this, we performed transurethral bladder tumor (TUR-MT). BC accounts for approximately 2.5% of all cases of metastatic bladder cancer in which the breast is the primary site of origin. Most secondary tumors arise by direct spread from another pelvic neoplasm, such as sigmoid colon, prostate, or cervical cancers. Metastases from distant organs are rarely reported in the literature; the most common are stomach, lung, and melanoma. Metastasis to the bladder after BC is rare and may occur many years later. Although the majority of cases are of the lobular subtype, metastasis can also occur in other subtypes. It may be asymptomatic or manifest as hematuria and voiding problems. Diagnosis involves imaging with ultrasound and magnetic resonance imaging, cystoscopic biopsy, and TUR-MT sampling.
