Tuğba GÜLER GUNT, Demet Funda BAŞ, Ufuk ŞENER, Ümit BELET
Forbes Tıp Dergisi - 2026;7(1):60-68
Objective: Mechanical thrombectomy is an effective treatment method for stroke patients with large vessel occlusion. Hemorrhagic transformation and edema can be observed during patient follow-up after mechanical thrombectomy. Transcranial Doppler (TCD) is a method used to evaluate hemodynamic changes following endovascular treatment (EVT), and the examination of patients with TCD contributes to the assessment of early neurological deterioration. Methods: Patients who presented to University of Health Sciences Türkiye, İzmir Tepecik Training and Research Hospital with acute ischemic stroke and underwent mechanical thrombectomy for anterior circulation occlusion were included in the study. Demographic data were recorded, along with initial and 24th-hour National Institutes of Health Stroke Scale (NIHSS) scores, post-procedural revascularization scores, and whether intravenous thrombolysis was performed. Patients were evaluated using TCD within the first 12 hours after EVT, and parameters in the ipsilateral and contralateral vessels were compared to examine their impact on hemorrhagic transformation and edema. Clinical outcomes were assessed using the 3-month modified Rankin scale (mRS). Results: The pulsatility index, peak systolic velocity, and end-diastolic velocity on TCD examination did not significantly affect hemorrhagic transformation and edema when comparing ipsilateral and contralateral vessels. A higher 24-hour NIHSS score was significantly associated with hemorrhagic transformation. Patients with edema were found to have higher mRS scores and an association with clinical outcomes. Conclusion: In our study, the evaluation of early clinical response by TCD examination after mechanical thrombectomy did not demonstrate a significant contribution.
