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RENAL MICROSPORIDIOSIS IN PEDIATRIC BONE MARROW TRANSPLANT RECIPIENTS: A CASE SERIES

SALONİ SHAH, SHEBA SWEETLİNE JAC OB, RAMA MANİ, ASHOK PARAMESWARAN, SUNİL KUMAR, RAJEEV A ANNİGERİ, RAJA MAHESH, RAMYA UPPULURİ

Türk Patoloji Dergisi - 2020;36(1):68-72

Department of Histopathology, Apollo Hospitals, CHENNAI, TAMIL NADU, INDIA

 

Microsporidiosis is a rare, but emerging opportunistic infection in solid organ transplant and stem cell transplant recipients. Renal involvement in microsporidiosis is very rarely seen in these recipients. We describe two cases of pediatric renal microsporidiosis, diagnosed on renal biopsies, following bone marrow transplantation presenting as severe acute kidney injury. The first patient died, whereas the second survived due to early diagnosis based on high index of suspicion and prompt treatment with Albendazole. We believe these are the first such reported cases of renal microsporidiosis in pediatric bone marrow transplant recipients.