ŞEFİKA AKYOL, NECDET ARDA ERDOĞMUŞ, MUSTAFA ALTAY ATALAY, ZEHRA FİLİZ KARAMAN, ALPER ÖZCAN, İBRAHİM KAFADAR, KEMAL DENİZ, AYŞE NEDRET KOÇ, EKREM ÜNAL
Trends in Pediatrics - 2024;5(3):101-104
Invasive fungal infections are important causes of mortality and morbidity in immunodeficiencies, hematological malignancies, and transplant recipients. There is scarce information in the literature about the diagnosis, treatment methods, and management. Herein, a unique involvement site of invasive fungal infection caused by Aspergillus flavus in the nadir of the induction chemotherapy of a 13-year-old boy with the diagnosis of acute lymphoblastic leukemia is presented. Despite prolonged intravenous antifungal therapy, the patient exhibited an inadequate response. As a result, intra-articular antifungal treatment was implemented alongside curettage and joint space irrigation. These additional interventions led to significantly improved clinical outcomes. Since fungal osteomyelitis can be an important cause of mortality and morbidity in immunosuppressed patients, prompt diagnosis and multidisciplinary treatment are crucial.
