AHMET C ÇALIŞKAN, SERDAR OĞUZ, H LEVENT KESKİN, ALPTEKİN ALAGÖZ, ŞEVKİ ÇELEN, HÜSEYİN DUMANLI
Gynecology Obstetrics & Reproductive Medicine - 2004;10(2):123-126
OBJECTIVE: The aim of this study was to evaluate the value of transvaginal ultrasonography (TVUS) and uterine artery resistance indices (RI) in the preoperative detection of myometrial invasion in endometrial carcinoma. STUDY DESIGN: Fifty-four patients with endometrial carcinoma underwent TVUS and doppler flow velocitometry studies. During these studies presence and depth of myometrial invasion and resistance indices of uterine arteries were noted. These findings were correlated with pathological findings obtained by surgical staging. Diagnostic accuracies of these variables in detecting deep myometrial invasion were assessed with the use of histological findings. RESULTS: All patients with grade 3 tumors (n=8) had deep myometrial invasion. 90% of patients with grade 1 tumors (n=21) had no or superficial myometrial invasion. The mean RI of deep invasion were significantly lower than patients with lesser degrees of invasion (0.436±0.11) vs 0.74±0.12). In identifying myometrial invasion by TVUS, sensitivity, specifity, positive predictive value and negative predictive value were 88%, 68%, 70% and 90%, respectively. CONCLUSION: Our findings indicate that TVUS may be useful for diagnosis of myometrial invasion in endometrial cancer. Between patients with deep and lesser degrees of invasion, there was an obvious overlaping in tumor grade and uterine artery RI values.
