FATMA EBRU ALGUL, HATİCE TOSUN
Annals of Clinical and Analytical Medicine - 2024;15(2):85-88
Aim: In this study, we aimed to investigate the relationship between migraine and serum adropin levels. Material and methods: This is a randomized control study. The study was conducted for 6 months starting from January 2021. Fifty-four migraine patients were selected for the study as a case group and matched with 35 healthy participants for the control group. We compared serum adropin, high-density lipoprotein (HDL-C), low-density lipoprotein (LDL-C), total cholesterol (TC) and triglyceride (TG) concentration and body-mass index (BMI) between the case and control groups. In addition, the relationship between migraine disease duration, monthly pain frequency and pain duration, and serum adropin level in the patient group was analyzed. Results: There was no significant difference between the two groups regarding age, gender, triglyceride, LDL-C, HDL-C, BMI levels and serum adropin levels (p<0.05). Also, there was no significant difference in migraine disease duration, frequency of headache (within a month) and headache duration depending on serum adropin levels. A negative correlation was determined between adropin levels and age and BMI (p<0.05). Discussion: Serum adropin concentrations are not associated with migraine in our population. Besides, serum adropin levels decrease with increasing BMI and with age. With this knowledge, however, it is difficult to make a definitive conclusion. Further studies with larger populations are needed.
