Arzu AKGÜL, Neriman Sıla KOÇ
The Journal of European Internal Medicine Professionals - 2026;4(1):41-42
Electrolyte disturbances are common in patients followed in intensive care units (ICU). With the increasing use of fosfomycin for multidrug-resistant infections, hypernatremia has emerged as a clinically significant problem. We present two illustrative ICU cases to highlight this underrecognized yet preventable complication. Each gram of intravenous fosfomycin disodium contains about 0.33 g of sodium, which can precipitate iatrogenic hypernatremia, particularly in critically ill patients. Early recognition and interdisciplinary collaboration are essential to minimize morbidity and improve outcomes.
