Ali Turunç, Mert Deniz Savcılıoğlu, Oğuz Kaan Polat, İrfan Veysel Düzen, Murat Taner Gülşen, Seval Kul, Sezgin Barutçu
Anatolian Current Medical Journal - 2025;7(6):792-798
Aims: This study aimed to evaluate whether subclinical cardiac involvement in patients with inflammatory bowel disease (IBD) can be detected early using strain echocardiography and to assess the relationship between disease activity and myocardial strain. Methods: A total of 40 patients with active IBD (22 with Crohn's disease, 18 with ulcerative colitis) were included. Global longitudinal strain (GLS) was measured by echocardiography during the active disease phase and after achieving remission. Strain values were compared between active and remission periods. Results: There was no statistically significant difference in GLS values between active and remission phases in the overall group or subgroups. However, strain improvement was more pronounced in female patients and non-smokers during remission. Conclusion: Although cardiac strain measurements did not significantly differ between disease phases, the findings suggest a potential impact of sex and smoking status on myocardial function in IBD. Strain echocardiography may help detect early cardiac involvement in selected patients.