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STUDY THE GENETIC VARIATIONS OF GRIAS GENES TO INVESTIGATE ASSOCIATION TO METHAMPHETAMINE ADDICTION

MARWA M AL ATTAR, SALWA J AL AWADİ

International Journal of Medical Biochemistry - 2025;8(3):205-211

Department of Biology, College of Science, Mustansiriyah University, Baghdad, Iraq

 

Objectives: Drug addictions are chronic complicated disorders characterized by the repeated and irresistible intake of specific drugs that produce transient bliss. Methamphetamine, an amphetamine derivative, is an addictive psychostimulant substance used all over the world, especially in South East Asia. Chronic Methamphetamine consumption not only causes dependence but also frequently promotes psychotic symptoms, auditory hallucinations, and paranoid delusions, which are similar to the positive symptoms of schizophrenia. This study looked at the genetic variation of the GRIA1 and GRIA3 genes to see if they were associated with methamphetamine addiction in Iraqi males