Ayşe BURAN, Hüseyin ALTAŞ, Yeşim ÖZKAYA UÇAR, Abdurrahman Alp TOKALIĞLU, Gülşah Tiryaki GÜNER, Okan AYTEKİN, Fatih KILIÇ, Taner TURAN
Journal of the Turkish-German Gynecological Association - 2026;27(2):120-124
Objective: To evaluate pathological findings in patients positive for human papillomavirus (HPV)-31. Material and Methods: This retrospective study included patients evaluated in a tertiary colposcopy clinic. The 3,546 patients tested for high-risk HPV were evaluated from September 2019 to December 2023. The study comprised 130 (3.7%) patients who tested positive for HPV-31. Isolated HPV-31 positivity indicated the presence of HPV-31 alone. Combined positivity indicated coexistence with other high-risk HPV types. If the following lesions were positive, high-grade squamous intraepithelial lesions (HSILs), adenocarcinoma in situ, microinvasive cancer, and cervical cancer, we classified the final pathology as >=HSIL. Statistical analysis was performed using IBM SPSS Statistics version 20.0. Results: The mean age was 44.4+/-9.24 years. Isolated HPV-31 positivity was present in 69 (53.1%) patients. The final pathologic result was >=HSIL in 9 (6.9%) patients, with only 1 (0.8%) patient had squamous cell cervical cancer. No significant association was observed between HPV-31 positivity type (isolated or combined) and >=HSIL (respectively, 7.2% vs. 6.6%; p=0.578). Conclusion: Approximately 7% of women positive for HPV-31 have HSIL and higher lesions. The isolated or combined HPV-31 positivity does not affect the existence of HSIL or higher lesions.
