MUNTADHER JABER, SADA GHALİB TAHER RİYADH RASHİD HAMEED SAJJAD MOHAMMED ZORAH DOHA JEHAD MOHAMMAD ADYAN NAFEA ABBAS FALAH HEREZ MADHLOOM ALRABEA SAMER KAREEM HANOON
Journal of Research in Pharmacy - 2025;29(5):1890-1895
Calcium supplements are commonly used by athletes, and they are also used to treat certain bone ailments, however their cardiovascular safety is still debated. This study was designed to investigate the effect of calcium supplements on troponin variables in athletes as well as those with bone diseases. The current study is case control research included 180 participants (60 patients with bone problems, 60 athletes who use calcium supplements, and 60 healthy control subjects who do not take calcium supplements) and the levels of calcium and troponin measured for all subjected group. The results showed that serum calcium levels in athlete’s participants were significantly higher than patients with bone diseases and healthy control subjects respectively (10.13 ± 1.2 vs 9.62 ± 0.92 and 8.57± 0.64, respectively). Also, the calcium levels in patients with bone diseases was significantly higher than healthy control subjects P< 0.001). Serum Troponine concentrations in patients with bone diseasesi and athletes participants were significantly higher than controls (0.22 ± 0.07 and 0.21 ± 0.07 vs 0.06 ± 0.01, respectively, P>0.001). Results showed that the Troponin levels correlate directly with serum calcium among study group which might be referred to that this condition enhances production of Troponin in relation to serum calcium which in turn affected by the calcium supplement administered that linked to a higher risk of myocardial infarction which lead to conclude that it is important to utilize calcium supplements sparingly and aim to get the majority of the necessary daily intake of calcium from food sources.
