Mehmet Reşit Sönmez, Mürşit Dincer, İsa Caner Aydin, Mustafa Duman, Erdal Polat
Laparoscopic Endoscopic Surgical Science - 2025;32(3):133-143
Introduction: There are conflicting results in studies regarding the effect of laparoscopic surgery on postop-erative complications in colorectal cancer patients. This study aims to evaluate the effect of laparoscopic surgery on major complications in patients undergoing surgery for colorectal cancer. Materials and Methods: A retrospective review was conducted on 370 patients who underwent oncologic surgery for colorectal cancer at Kartal Koşuyolu High Specialization Hospital between 2013 and 2022. Pa-tients with missing data were excluded, and a total of 257 patients were included in the study. Patients were divided into two groups based on the development of major or no complications, and clinical and patho-logical data were compared. The relationship between surgical method (laparoscopic vs. conventional) and complications was evaluated using multivariate Cox regression analysis. Results: Major complications occurred in 106 of the 257 patients included in the study. The rate of major complications was found to be significantly lower in patients who underwent laparoscopic surgery (12.2% vs. 30.4%; p<0.001). In univariate analysis, conventional surgery (OR: 3.134; p<0.001), high body mass index (p=0.046), and history of Chronic Obstructive Pulmonary Disease/asthma (p=0.046) were found to be as-sociated with major complications. In multivariate analysis, only conventional surgery was identified as an independent risk factor (OR: 2.969; p=0.002). Conclusion: Laparoscopic surgery significantly reduces the risk of major complications in patients with col-orectal cancer and can be considered a safe and effective surgical option, even in patient populations with high comorbidities.
