Elvin Halili ÇELENK
Van Medical Journal - 2026;33(4):430-436
Introduction: To compare pupillometric, aberrometric, and biometric parameters among low, moderate, and high myopia groups and assess relationships between pupil parameters and higher-order aberration (HOA) components. Materials and Methods: This cross-sectional study included 60 eyes classified by spherical equivalent (SE) as low myopia (-0.50 to -3.00 D; n=33), moderate myopia (-3.01 to -6.00 D; n=15), and high myopia (<-6.00 D; n=12). Corneal topographic and aberrometric measurements were obtained using a corneal topography system, and biometric measurements using an optical biometry device (Topcon Corp., Tokyo, Japan). Examinations were performed under standardized illumination by the same examiner. Three consecutive measurements were averaged. Group comparisons used the Kruskal-Wallis test, with Holm-adjusted post hoc analyses where appropriate. Correlations were assessed using Spearman's rank correlation analysis. Results: SE was the only variable that differed significantly among groups (p = 3.86 x 10?¹¹), and post hoc analysis confirmed significant differences between all group pairs. No significant between-group differences were found for age, photopic pupil diameter, mesopic pupil diameter, pupil difference, coma, spherical aberration, total HOA, axial length, or sex distribution. Correlation analyses did not reveal a strong or consistent association between pupil parameters and HOA components. A positive correlation between mesopic pupil diameter and coma was observed in the moderate-myopia group (rho = 0.643, p = 0.0098), but lost significance after multiple-comparison correction. Discussion and Conclusion: Myopia groups differed significantly only in SE. Other parameters showed no significant group differences, and no pupil-HOA correlations remained significant after multiple-comparison correction.
