BEDİH BALKAN, BARIŞ TİMUR
Comprehensive Medicine - 2025;17(1):1-7
Objective: Various hemogram parameters have been used for predicting mortality in intensive care. In this study, the effect of new inflammatory biomarkers such as mean platelet volume, platelet/lymphocyte ratio, and neutrophil/lymphocyte ratio on early mortality was researched in patients with chronic renal failure, who had a cardiac surgery operation. Materials and Methods: All the patients with preoperative chronic renal failure who underwent on-pump or off-pump cardiac surgery in our clinic between September 2016-September 2019 were examined. Patients’ demographic data, preoperative hemoglobin, platelet/lymphocyte, neutrophil/lymphocyte, and mean platelet volume and postoperative hemoglobin, platelet/lymphocyte, neutrophil/lymphocyte and MPV were reviewed. Whether there is a difference in on-pump and off-pump surgeries on the matter and their 30-day surgical mortality were assessed in intensive care follow-ups. Results: Of the patients included in the study within the preoperative period, 74 (60%) had DM and 94 (76.4%) were hypertensive. The mean duration of the patients’ hospitalization was found as 13.88±2.4 days. Thirty-day surgical mortality: 30 (24.4%); preoperative and postoperative, platelet/lymphocyte, neutrophil/lymphocyte of the patients did not appear significant. It was found that MPV in the on-pump group was significantly higher in both preoperative and postoperative values than in the off-pump group. Preoperative PLR and NLR values were significantly lower (p< 0.05) in the off-pump group. Conclusion: MPV is an important marker in determining the postoperative mortality in patients with chronic renal failure who had cardiac surgery.
