Burcu ÖZBAKIR
Cyprus Journal of Medical Sciences - 2026;11(5):424-429
BACKGROUND/AIMS: Oocyte donation is a popular form of in vitro fertilisation (IVF) treatment for health tourists worldwide and in Northern Cyprus. Patients with various medical conditions requiring this treatment have diverse demographic profiles and clinical findings. Viewing patients holistically may provide new insights into treatment. MATERIALS AND METHODS: This retrospective study included patients who underwent oocyte-donation IVF at the Near East University Hospital IVF Centre in Northern Cyprus between October 2021 and March 2024. The ages of female and male patients at the time of treatment, their smoking and alcohol habits, body mass index (BMI), endometrial parameters, transfer quality, sperm parameters, donor age and BMI, and oocyte and embryo evaluation parameters were assessed. RESULTS: The mean ages of female and male patients were 41.91+/-6.78 and 41.47+/-9.21, respectively, with most being overweight. Most patients preferred two-embryo transfers on day five of embryo development. While 18.1% of patients wished to add preimplantation genetic diagnosis to their treatment, 29.4% opted for sperm microchipping, and 11.3% chose sperm donation. The endometrial rim was thicker in younger female patients (p<0.001) and in non-smoking female patients (p=0.021). A trilinear pattern of the endometrium was observed more frequently in younger (p=0.001), non-smoking (p=0.031), and non-alcohol-consuming (p=0.014) patients. CONCLUSION: Personalised treatments require evaluation of demographic and clinical variations among patients with diverse profiles and findings. This methodology may enable more effective modifications to clinical outcomes.
