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THE MORPHOLOGY AND NEURONAL GLIAL CORRELATIONS OF THE SPINAL CORD POSTERIOR HORNS OF HUMAN EMBRYOS

SERGİİ VİKTOROVYCH VERNYGORODSKYİ, VOLODYMYR SEMENOVYCH SHKOLNİKOV, SVİTLANA OLEKSANDRİVNA PRYKHODKO

International Medicine - 2021;3(3):93-100

Department of Pathological Anatomy, Vinnytsia National Pirogov Memorial Medical University, Vinnytsia, Ukraine

 

Background: This research examines the morphology and neuronal glial correlations of human spinal cord posterior horns formations in the embryonic period of ontogenesis. Methods: 29 human embryos with a gestational age of 5 8 weeks were involved in the investigation, without visible damages and abnormalities in the development of the brain and spinal cord. Anatomical, histological, immunohistochemical, morphometric and statistical methods were used. Results: The glial index in 5 6 week human embryos in the posterior horns of cervical segments made 1.6, in thoracic segments – 1.4, in lumbar segments – 1.5, and in sacral segments – 1.3. In 6 7 week human embryos, on the lateral surfaces of the neural tube between alar and basal plates, the sulcus limitans is still preserved. The glial index in 7 8 week human embryos of posterior horns of cervical segments made 1.7, in thoracic segments – 1.5, in lumbar segments 1.6, and in sacral segments – 1.4. In 7 8 week embryos, the basal and alar plates are not distinguished anymore, that is why the terminal sulcus is absent. Conclusions: The glial index of the posterior horns of all the segments along with the spinal cord increases by the 6th 7th week, and remains unchanged by the beginning of the gestational period (before the 8th week).