Erkan Arslan
Eurasian Journal of Critical Care - 2025;7(3):59-61
This letter to the editor provides a urological perspective on a recent study investigating gender-related biochemical parameters in acute kidney injury (AKI). AKI is traditionally classified as prerenal, intrinsic renal, or postrenal. While most studies emphasize prerenal and intrinsic etiologies, postrenal causes represent a clinically significant and often reversible subset, particularly in elderly men. Common etiologies include benign prostatic hyperplasia, prostate cancer, bladder tumors, ureteral calculi, and strictures. In this context, elevated serum creatinine levels in men may not only reflect differences in muscle mass but also a higher burden of obstructive pathology. Timely diagnosis with imaging and prompt decompression procedures can lead to full recovery of renal function in postrenal AKI. Therefore, systematic evaluation for obstructive causes should be an integral part of the diagnostic approach, especially in elderly male patients.
