Muhammed AKAY, Nazire Belgin AKILLI, Ramazan KÖYLÜ
Eurasian Journal of Emergency Medicine - 2026;25(1):394-402
Aim: Our objective was to examine ocular ultrasonography findings in sepsis-related encephalopathy and assess its relationship with mortality. Materials and Methods: Male and female patients over the age of 18 who were diagnosed with septic encephalopathy and whose relatives or self-consent were given to participate in the study were included in the study. Healthy adult patients over 18 years of age were included in the control group. Demographic and laboratory data, glasgow coma scale, Sequential Organ Failure Assessment (SOFA), quick SOFA, APACHE II scores, ocular ultrasonographic results and death status were noted. Results: 100 patients and 30 control groups were included in the study. While the right optic nerve sheath diameter (ONSD) values were 0.49+/-0.006 cm in the patient group and 0.40+/-0.02 cm in the control group, the left ONSD values were 0.48+/-0.006 cm in the patient group and 0.41+/-0.02 cm in the control group. While the right optic disc elevation (ODE) values were 0.009+/-0.03 cm in the patient group and 0.00+/-0 cm in the control group, the left ODE values were 0.005+/-0.01 cm in the patient group and 0.00+/-0 cm in the control group (p<0.05). Sensitivity for left ONSD >0.48: 72.2 (46.5-90.3), specificity: 74.3 (63.6-83.4), positive predictive value: 38.2 (28-49.7), negative predictive value: 92.4 (85.1-96.3) (area under the curve 0.75 and p: 0,0003). Conclusion: ONSD and ODE are enlarged in patients with septic encephalopathy compared to healthy controls. Inpatients with septic encephalopathy, ONSD and ODE measurement can give preliminary information about intracranial pressure, clinical course and mortality.
