THE RETROCONVERSION OF IMMATURE TERATOMA WITH CHEMOTHERAPY: A CASE REPORT AND REVIEW OF THE LITERATURE

OKTAY BOZKURT, HALİT KARACA, ERAY EROĞLU, SÜMEYRA KOYUNCU, VELİ BERK, MEVLÜDE İNANÇ POLAT, AYŞE OCAK DURAN, ERSİN ÖZASLAN, MELİKE ORDU, GÜLŞAH ÇUBUKÇU, METİN ÖZKAN

Journal of Clinical Practice and Research - 2014;36(3):136-138

Department of Medical Oncology, Erciyes University Faculty of Medicine, Kayseri, Turkey

 

Immature ovarian teratoma is a rarely seen germ cell tumor. Although testicular germ cell tumors and their association with chemotherapeutic retroconversion have been reported at a substantial rate of 2%-8% in the literature, the retroconversion of immature ovarian teratoma to mature teratoma is quite uncommon. It is important to reveal this conversion by biopsy for establishing a subsequent treatment chart of patients. A 45-year-old female patient was operated on due to immature ovarian teratoma. Then, she was re-operated on, because local recurrence occurred during the drug-free follow-up period, and systemic chemotherapy was administered. Liver metastasis was detected after chemotherapy, and the liver biopsy demonstrated a mature teratoma. This case is presented in this paper.