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THE ROLE OF ANTI-MULLERIAN HORMONE IN DETERMINING OVARIAN RESERVE IN PATIENTS WITH ENDOMETRIOMA AND BENIGN CYSTS

ERGÜL DEMİRÇİVİ, DUYGU VARDAĞLI, ALİ İSMET TEKİRDAĞ, ÖZGÜR AKBAYIR, AHMET GÜLKILIK, BEYHAN ÖMER, SEZAİ SAHMAY

Zeynep Kamil Medical Journal - 2024;55(1):29-33

Department of Obstetrics and Gynecology, Istanbul Medeniyet University, Istanbul, Turkey

 

INTRODUCTION: Our aim was to determine the effects of endometrioma by itself and its surgery on ovarian reserve via pre- and postoperative serial measurements of Anti-Mullerian Hormone (AMH) in patients with endometrioma and benign cysts. METHODS: Our study was conducted at an education and research hospital as a prospective controlled clinical trial. Participants were divided according to their diagnosis into endometrioma and non-endometrioma groups. Serial blood samples of the patients for serum AMH levels were collected preoperatively, and postoperatively at the first week, first month, and third month, respectively. Results: A total of 46 patients (25 for the study and 21 for control groups) were included in the study. The mean age of our patients was 31.8±5.57 in the endometrioma group and 29.38±8.64 in the control group. The AMH value was lower in the endometrioma group, but the difference did not reach statistical significance (p>0.05). However, in the postoperative AMH levels measured at the 1st week, 1st month, and 1st year, the values were significantly higher in the non-endometrioma group compared to the endometrioma group (p<0.05). DISCUSSION AND CONCLUSION: According to our study, we can conclude that endometrioma surgery affects ovarian reserve significantly and more negatively than benign cystectomies.