THE ROLE OF LIPID PROFILE AND INFLAMMOTRY MARKERS IN DIFFRENTIATING BETWEEN FOCAL AND GENERALIZED TYPES OF SEIZURES IN PEDIATRIC EPILEPSY PATIENTS

SERAP BİLGE, HÜSEYİN BİLGİN

The European Research Journal - 2025;11(5):934-943

Department of Pediatric Neurology, Ministry of Health, Diyarbakır Children’s Hospital, Diyarbakır, Türkiye

 

Objectives: Seizures result from excessive and abnormal neuronal excitation, accompanied by pathophysiological processes such as inflammation, oxidative stress, and apoptotic cell death. Previous studies have demonstrated that patients with epilepsy often exhibit dysregulated inflammatory, vascular, and metabolic pathways, with certain seizure types associated with high pro-inflammatory cytokines. We aimed to investigate whether lipid profile parameters and inflammatory markers can be used to differentiate between focal and generalized seizures in pediatric epilepsy patients.