Jasiya QADIR, Sabhiya MAJID, Suhail Shafi LONE, Mumtaz Din WANI, Mosin Saleem KHAN
Turkish Journal of Oncology - 2026;41(1):1-9
ARID1A has emerged as a pivotal tumour suppressor gene, essential to chromatin remodelling and gene regulation. In colorectal cancer (CRC), dysregulated ARID1A gene expression triggers uncontrolled cellular growth and chemoresistance. This study investigates the spectrum of ARID1A variants in exon-9, its mRNA expression in CRC tissues and potential correlations with clinicopathological parameters.
