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ADR Yönetimi

THERAPY RESISTANT IDIOPATHIC SCLEREDEMA: AN UNDERLYING PATHOLOGY NOT ALWAYS PRESENT

MELİKE KALFA, HAYRİYE KOÇANAOĞULLARI, FİGEN YARGUCU ZİHNİ, GONCA KARABULUT, HAKAN EMMUNGİL, VEDAT İNAL

European Journal of Rheumatology - 2015;2(4):163-164

Department of Internal Medicine, Division of Rheumatology, Ege University Faculty of Medicine, İzmir, Turkey

 

Scleredema is a rare connective tissue disorder of unknown pathogenesis. Three types of scleredema have been described, based on its association with postinfection, monoclonal gammopathy and diabetes mellitus. We report herein a case of scleredema which the diagnosis didn’t get specified. The patient was followed regularly for 13 years and did not respond to various combinations of immunosuppressants and psoralen plus ultraviolet A therapy. Treatment of scleredema is quite difficult and of limited success. At present, there is no proved treatment for this disease.