Hüseyin Kaya, Arman Vahabi, Ali Engin Daştan, Tahsin Sami Çolak, Burçin Keçeci, Dündar Sabah
Acta Orthopaedica et Traumatologica Turcica - 2025;59(6):477-484
Objective: Total femoral replacements for oncological indications are a rare indication, and there is limited data on functional outcomes, complications, and implant survival rates. The purpose of this study was to investigate functional outcomes, the rate and nature of complications associated with this technique, and the survival rates of the implant used. Methods: This is a retrospective case series from a single subspeciality orthopedic oncology unit in an urban referral center that evaluated patients treated between January 2000 and May 2023. A total of 27 patients were included in the final analyses. The Musculoskeletal Tumor Society (MSTS) scoring system was used for functional evaluation. Results: The median MSTS score at the most recent follow-up was 21 (range: 17-23). A total of 16 complications occurred in 13 patients. Only one of these complications was an intraoperative issue. Ten of the 16 complications necessitated one or more secondary surgical interventions. The most common complication was infection, occurring in 8 patients. Conclusion: Total femoral replacement is reserved for distinctly specific oncological indications, where other more biological reconstruction methods are not feasible. This technique could yield satisfactory functional outcomes, along with a favorable implant survival rate and complication-free survival rate at mid-term.
