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ADR Yönetimi

TOWARDS A PREDICTED ANTI-AGING MOLECULAR TARGETS OF ASIATICOSIDE BASED ON BIOINFORMATICS ANALYSIS

MARİA VİOLİTA SEKAR AYU KENCANA, K ARİEX WİDYANTARA, YOSEF CHRİSTİAN, BAKTİ WAHYU SAPUTRA, AGUSTİNA SETİAWATİ

International Journal of Medical Biochemistry - 2025;8(2):78-88

Department of Pharmaceutical Biology, Faculty of Pharmacy, Sanata Dharma University, Yogyakarta, Indonesia

 

Objectives: Human skin, the largest organ, serves as a critical barrier against environmental damage and microbial invasion. The skin aging process leads to collagen degradation, reduced elasticity, and wrinkle formation, influenced by intrinsic and extrinsic factors. This process has driven significant interest in the anti-aging market, which is expected to grow to $44.5 billion by 2030. Asiaticoside (AS) has exhibited anti-aging properties by promoting collagen synthesis and fibroblast proliferation.